The influence of polymorphonuclear leukocytes and macrophages on the growth of lymphocytes and fibroblasts in vitro. |
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| Authors: | H Tchórzewski A Denys S Lipiński |
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| Affiliation: | 1. Department of Internal Medicine, UMMS-Baystate Medical Center, Springfield, MA, USA;2. Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, USA;3. Department of Cardiology, Cleveland Clinic, Weston, FL, USA;4. Department of Cardiology, UMMS-Baystate Medical Center, Springfield, MA, USA;1. Huntsman Cancer Institute, University of Utah, Salt Lake City, UT;2. Division of Hematology and Hematologic Malignancies, University of Utah, Salt Lake City, UT;3. Molecular Biology Graduate Program, University of Utah, Salt Lake City, UT |
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| Abstract: | The influence of polymorphonuclear leukocytes (PMNL) and macrophage plasma, nuclei and lysosome extracts have been tested on lymphocytes and fibroblasts growth in vitro. The stimulatory activity of PMNL lysosomes has been shown on lymphocyte and fibroblast growth. The macrophage lysosomes have shown a similar but lower activity. The role of lysosomes has been suggested in reparation and wound healing processes, presumably in inflammatory cell infiltrated regions. |
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