梅毒患者246例肝炎病毒标志物的检测

目的调查梅毒患者病毒性肝炎的感染情况。方法用酶联免疫吸附实验（ELISA）对246例梅毒患者（观察组）和307例健康体检者（对照组）的乙型肝炎病毒（HBV）两对半、丙型肝炎病毒抗体（抗-HCV）进行检测。结果观察组乙肝表面抗原（HBsAg）、抗-HCV的阳性率分别为16．26％、8．54％，均高于对照组的8．79％、2．93％，差异具有统计学意义（P〈0．05）；观察组“大三阳”指乙型肝炎病毒表面抗原（HBsAg）、己型肝炎病毒e抗原（HBeAg）、乙型肝炎病毒核心抗体（HBcAb）阳性]比例62．50％高于对照组29．63％，差异具有统计学意义（P〈0．05）。结论梅毒患者HBV、HCV感染率高于普通人群，应加强梅毒患者的肝炎标志物的检测。

Detection of hepatitis virus markers in patients with syphilis

Objective To investigate the status of hepatitis virus infection in syphilis patients. Methods Five HBV markers and anti - HCV antibody were detected in 246 patients with syphilis （observation group） and 307 healthy persons （control group） by enzyme linked immunosorbent assay （ELISA） . Results Among 246 syphililis cases, the positive rates of HBsAg and anti - HCV were 16.26% and 8.54% respectively, they were higher than those of control group （8.79% and 2.93% ）, and their difference was statistically significant between these two groups （ P 〈0.05）. The positive rate of HBsAg, HBcAb and HBeAg in observation group was 62.50%, and it was higher than that of control group （29.63%）, and there was statistically significant difference between these two groups （ P 〈 0.05 ）. Conclusion The infection rates of HBV and HCV in patients with syphilis are higher than those of ordinary persons. Detection of hepatitis virus markers in patients with syphilis should be strengthened.