| 重症急性胰腺炎早期液体复苏的临床研究 |
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| 引用本文： | 温尔刚,董科,余小炯. 重症急性胰腺炎早期液体复苏的临床研究[J]. 华西医学, 2009, 24(12) |
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| 作者姓名： | 温尔刚 董科 余小炯 |
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| 作者单位： | 四川省人民医院肝胆胰外科,四川成都,610072;四川省人民医院肝胆胰外科,四川成都,610072;四川省人民医院肝胆胰外科,四川成都,610072 |
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| 摘 要： | 目的:探讨急性重症胰腺炎(SAP)早期不同种类液体复苏对其预后的影响。方法:应用随机对照的方法,分别对2007年12月～2009年10月同期入院的48例SAP患者,随机分成两组,试验组和对照组。试验组第一周内液体复苏采用晶体液和人工胶体(羟乙基淀粉),对照组采用晶体液,其他治疗方法不变。然后统计其第一周死亡率、ARDS、多器官功能障碍综合征(MODS)发生率,对比两组患者呼吸频率、血氧饱和度和红细胞压积(HCT)差异,以及两组患者肠功能恢复时间、住院时间以及并发症发生率。结果:试验组的液体复苏较对照组显著改善SAP的各项指标(P<0.05)。血清乳酸水平(1.5±0.5)mmol/L,红细胞压积(HCT)为(32.4±6.9)%,ScvO2为(81.7±15.2)%,病死率8.3%,MODS发生率33.3%,结论:SAP早期联合应用晶胶体进行液体复苏可有效恢复循环血容量和防止体液潴留,显著提高其治愈率。
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| 关 键 词： | 胰腺炎 急性坏死性 液体治疗 |
Strategy of Fluid Resuscitation in the Early Stage of Severe Acute Pancreatitis |
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| WEN Er-gang; DONG Ke; YU Xiao-jiong. Strategy of Fluid Resuscitation in the Early Stage of Severe Acute Pancreatitis[J]. West China Medical Journal, 2009, 24(12) |
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| Authors: | WEN Er-gang DONG Ke YU Xiao-jiong |
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| Affiliation: | WEN Er-gang; DONG Ke; YU Xiao-jiong.Department of Hepatobiliary Pancreatic Surgery; Sichuang Province People; s Hospital; Chengdu Sichuan 610072; China; |
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| Abstract: | Objective: To investigate the optimal strategy of fluid resuscitation in the early stage of severe acute pancreatitis.Methods:Fourfy-eighs SAP patients who received treatment in our hospital from 12,2007 to 10,2009 were randomly divided into 2 groups(n=24) according to the different amounts of crystal and colloid in the daily resuscitation,including crystal group,combined group(the ratio of crystal to colloid was 2 to 1).The levels of hematocrit(HCT),saturation of central vein oxygen(ScvO2),serum lactic aci... |
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| Keywords: | pancreatitis acute necrotizing fluid therapy |
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