CRP在急性胰腺炎诊断中的临床价值研究

目的：动态监测急性胰腺炎（AP）患者外周血C-反应蛋白（CRP）水平,探讨CRP对AP的早期诊断与病情评估的参考价值。方法：分别检测75例SAP患者和75例MAP患者入院后第1、3、5、7、9天外周血CRP水平,并进行分析比较。结果：MAP组患者CRP高峰值出现在住院第3天,第7天开始下降,14天后恢复正常。而SAP组患者住院第1天即可出现CRP显著增高,且下降速度缓慢,在后期CRP仍可维持在一个较高水平。入院第1天,SAP组血清CRP水平均显著高于MAP组（P〈0.01）。轻症与重症组（无并发症或有并发症）之间患者血清CRP水平差异均有高度显著性（P〈0.01）。结论：动态监测CRP可作为AP早期诊断、疾病严重程度评估及预后判断的一个独立的衡量指标,值得临床推广应用。

CRP in the Diagnosis of Acute Pancreatitis Value

Objective：To dynamic monitoring of acute pancreatitis（AP） in patients with C-reactive protein（CRP） levels,CRP on the AP to explore the early diagnosis and prognostic evaluation of the reference value.Methods：75 cases of SAP patients were examined and 75 patients with mild acute pancreatitis（MAP） after admission in patients with CRP levels in peripheral blood 1,3,5,7,9 days,and conduct analysis and comparison of.Results：MAP peak value of CRP in patients in hospital the first 3 days.7 day drop in 14 days after return to normal.The SAP Group 1st day of hospitalization was significantly higher CRP can occur,and the rate of decline is slow,in the latter part of CRP can be maintained at a high level.Admission day 1,SAP serum levels of CRP were significantly higher than the MAP group （P0.01）.Between mild and severe group,no complications and complications in patients with serum CRP levels of SAP differences were highly significant（P0.01）.Conclusion：Dynamic monitoring of CRP can be used as AP early diagnosis,disease severity assessment and prognosis of an independent measure worthy of clinical application.