| NucliSens HIV-1 QT和Amplicor HIV-1 monitor1.5方法测定HIV-1病毒载量的比较研究 |
| |
| 引用本文： | 潘品良,许文燕,姚均,陶晓霞,裴丽健,蒋岩. NucliSens HIV-1 QT和Amplicor HIV-1 monitor1.5方法测定HIV-1病毒载量的比较研究[J]. 中华实验和临床病毒学杂志, 2007, 21(2): 177-179 |
| |
| 作者姓名： | 潘品良 许文燕 姚均 陶晓霞 裴丽健 蒋岩 |
| |
| 作者单位： | 100050,北京,中国疾病预防控制中心性病艾滋病预防控制中心参比实验室 |
| |
| 基金项目： | 克林顿基金中国艾滋病卫国际双便函项目资助（2004）649 |
| |
| 摘 要： | 目的进行NuchSens HIV-1 QT和Amplicor HIV-1 monitor 1．5检测相同临床样品HIV-1病毒载量值之间的比较研究。方法收集临床样本82份，使用两种方法测定病毒载量，对病毒载量值进行统计分析。结果未测到核酸的和两种方法病毒载量对数值之差小于0．5的占88．9％；用△log10 VL〈0．5的56份样本统计两种方法的相关性，相关系数为0．956。结论NucliSens HIV-1 QT和Amphcor HIV-1 monitor 1．5两种方法测定的HIV病毒载量值有很好的相关性。
|
| 关 键 词： | HIV-1 病毒载量 逆转录聚合酶链反应 核酸扩增技术 |
| 收稿时间： | 2006-12-29 |
| 修稿时间： | 2006-12-29 |
Comparison of NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 in detecting HIV-1 viral load |
| |
| PAN Pin-liang,XU Wen-yan,YAO Jun,TAO Xiao-xia,PEI Li-jian,JIANG Yan. Comparison of NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 in detecting HIV-1 viral load[J]. Chinese journal of experimental and clinical virology, 2007, 21(2): 177-179 |
| |
| Authors: | PAN Pin-liang XU Wen-yan YAO Jun TAO Xiao-xia PEI Li-jian JIANG Yan |
| |
| Affiliation: | Chinese Center for Disease Control and Prevention, Beijing 100050, China |
| |
| Abstract: | OBJECTIVE: To compare the results of detecting HIV-1 load by using NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 assays. METHODS: Eighty-two clinical samples were collected and HIV viral load was determined with the above-mentioned two methods. RESULTS: The number of samples in which values obtained by NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 differed by <0.5 log10 RNA copies/ml and in which the viral load was undetectable accounted for 88.9 percent of the measures. The correlation coefficient between the two methods was 0.956 in 56 samples of Deltalog10 VL<0.5. CONCLUSION: The results of HIV-1 viral load determination with the two methods are highly comparable. |
| |
| Keywords: | |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
