A randomized prospective trial comparing the levonorgestrel-releasing intrauterine system with thermal balloon ablation for the treatment of heavy menstrual bleeding |
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Authors: | Sérgio S de Souza Carolina P de Rezende Cícero AA Araújo |
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Institution: | a Clinics Hospital of the Federal University of Minas Gerais, Minas Gerais, Brazil b Department of Gynecology and Obstetrics, School of Medicine, Federal University of Minas Gerais, 30130-100 Belo Horizonte, Minas Gerais, Brazil |
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Abstract: | BackgroundUse of the levonorgestrel-releasing intrauterine system (LNG-IUS) was compared with thermal balloon ablation (TBA) for the treatment of heavy menstrual bleeding (HMB).Study DesignA prospective randomized trial comparing the LNG-IUS (n=30 women) and TBA (n=28 women).ResultsHemoglobin levels increased (p<.001) and blood loss was reduced (p<.001) in both groups after 1 year of treatment. Menstrual bleeding was less in the LNG-IUS group compared to the TBA group at 6 and 12 months of treatment (p=.035 and p=.048, respectively). Intermenstrual bleeding was significantly less in the TBA group at 6 months compared to the LNG-IUS group (p=.044); however, there was no significant difference at 12 months (p=.129). No difference was found in psychological aspects between pre- and posttreatment variables in either of the groups (p=.537).ConclusionsBoth the LNG-IUS and TBA appear to be effective in controlling HMB; however, posttreatment uterine bleeding patterns are different. |
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Keywords: | Heavy menstrual bleeding Thermal balloon ablation Levonorgestrel-releasing intrauterine system Endometrium |
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