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VIP方案加放射治疗晚期非小细胞肺癌的近期疗效观察
引用本文:蔡永清,白晓明.VIP方案加放射治疗晚期非小细胞肺癌的近期疗效观察[J].临床肿瘤学杂志,2000,5(3):190-191.
作者姓名:蔡永清  白晓明
作者单位:大连市中心医院肿瘤科
摘    要:目的:评估VIP方案化疗与放射治疗晚期非小细胞肺癌(NSCLC)的近期疗效。方法:观察1997年2月~1999年2月收治的33例晚期非小细胞肺癌患。化疗以VIP方案为主,2~4周期后行放射治疗,放疗剂量DT50~70Gy/5~7周。结果:完全缓解(CR)率为15.2%,部分缓解率(PR)为51.5%,总有效率(CR+PR)为66.7%。毒副反应主要为Ⅰ~Ⅱ度消化道反应、骨髓抑制及脱发。结论:VI

关 键 词:VIP方案化疗  放疗  晚期非小细胞肺癌

The observation of short term response with VIP chemotherapy plus radiotherapy for advanced non-small cell lung cancer
Cai Yongqing,Bai Xiaoming,Qian Zhiling.The observation of short term response with VIP chemotherapy plus radiotherapy for advanced non-small cell lung cancer[J].Chinese Clinical Oncology,2000,5(3):190-191.
Authors:Cai Yongqing  Bai Xiaoming  Qian Zhiling
Institution:Cai Yongqing,Bai Xiaoming,Qian Zhiling. Department oj Oncology,Dalian central hospital,Dalian 116033
Abstract:Objective: To evaluate the short term response of chemotherapy in combination with radiotherapy for advanced non-small cell lung cancer(NSCLC) . Methods: From February 1997 through February 1999, 33 patients with advanced NSCLC were entered into the study. The major regimn of chemotherapy was VIP, radiotherarpy was given after 2 ~ 4 cycles of the chemotherapy. The radiation does ranged from 50~70Gy/5~7 weeks. Results:The complete response(CR) rate was 15.2%, and partial response (PR) was 51.5%, the overall effective (CR PR) rate was 66.7% . The major toxic effects were gastrointerstinal tract reactions, myelosuppression and alopecia. Conclusions:The short term response of VIP regimen chemotherapy combination with radiotherapy for patients with advanced NSCLC is prefirable and tolerable toxicity.
Keywords:VIP Chemotherapy  Radiotherapy  Advanced non small cell lung cancer
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