| 洛阳地区2600例遗传咨询者外周血染色体分析 |
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| 引用本文： | 白静,王亚男,郭杰,梁航. 洛阳地区2600例遗传咨询者外周血染色体分析[J]. 中国优生与遗传杂志, 2010, 0(1): 47-48 |
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| 作者姓名： | 白静 王亚男 郭杰 梁航 |
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| 作者单位： | 洛阳市妇女儿童医疗保健中心生殖研究所; |
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| 摘 要： | 目的通过对患者外周血染色体分析,探讨染色体异常与疾病的关系。方法按常规方法收获外周血淋巴细胞及制片,G显带后分析染色体核型。结果2600例患者共检出183例异常染色体核型,异常率8%,其中21-三体核型84例,易位24例,倒位染色体核型16例,性染色体异常及其它异常59例。结论染色体异常是引起智力低下、不孕不育、习惯性流产、发育畸形的主要原因之一,染色体检查对提高人口素质有重要意义。
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| 关 键 词： | 染色体 异常核型 遗传咨询 |
Chromosomal analysis for 2600 cases genetic consultant in Luoyang area |
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| BAI Jing,WANG Ya-nan,GUO Jie,LIANG Hang.. Chromosomal analysis for 2600 cases genetic consultant in Luoyang area[J]. Chinese Journal of Birth Health & Heredity, 2010, 0(1): 47-48 |
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| Authors: | BAI Jing WANG Ya-nan GUO Jie LIANG Hang. |
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| Affiliation: | BAI Jing,WANG Ya-nan,GUO Jie,LIANG Hang.(The Reproductive Institute of Luoyang Materal , Child Health Hospital,Luoyang,471000) |
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| Abstract: | Objective:To study the relationship between the abnormal karyotype and the disease with karyotype analysis.Methods:Chromosomes were prepared according to the human body lymphocyte culture method,and karyotype analysis were done after G-banding.Results:183 samples were detected in 2600 patients,the rate of abnormality is 8%.84 cases were trisomy 21 karyotype,24 cases were the transposition,16 cases were chromosome inversion,59 cases were sex chromosomal abnormalities and other abnormal karyotypes.Conclusion:... |
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| Keywords: | Chronmosome Abnomal karyotype Genetic consuling |
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