白癜风负压吸疱自体表皮移植的影响因素

负压吸疱自体表皮移植是目前广泛使用的稳定期白癜风治疗方法之一,具有成功率高,并发症少的优点,其疗效受多种因素影响.主要包括:负压吸疱条件如吸疱部位、温度、压力、吸疱时间等;受皮区的磨削技术;术中、术后汴意事项;术前或术后选择联合的不同治疗方法.这些因素之间亦相互作用,影响皮片内黑素细胞的含量和成活率,进而影响皮肤移植区着色程度和色素扩展范围.

Influencing factors of autologous epidermal graft by suction blister in the treatment of vitiligo

Autologous epidermal graft by suction blister is a common treatment for stable vitiligo with high success rate and less complications. Its efficacy is affected by various factors, including the selection of donor site, temperature, negative pressure, induction time of suction blister, strategies for the removal of epidermis in depigmented area before transplantation, distinguishing of epidermis from dermis during the process of transplantation, etc. Besides, combined therapy such as PUVA could improve the clinical outcome of transplantation. These factors, interacting with each other, affect the concentration and survival rate of melanocytes in skin graft, and in turn impact the repigmentation degree and extent.