60角膜缘干细胞移植治疗复发性翼状胬肉的临床研究

目的探讨改进显微手术切除联合自体角膜缘上皮干细胞移植术治疗复发性翼状胬肉的临床疗效。方法88例（88眼）复发性翼状胬肉，随机分别采用单纯显微手术切除方法（A组）和显微手术切除联合自体角膜缘移植术（B组），各44例（44眼）。术后随访4～28（平均14．30±7．42）。结果A组真性胬肉复发9眼，复发率20．45％；B组真性胬肉复发3眼，复发率为6．82％。两组复发率差异有统计学意义（X^2=1．137，P〈0．05）。结论改良的显微手术切除联合自体角膜缘上皮干细胞移植术是治疗复发性翼状胬肉的理想方法。

Clinical Research on Autografting of Limbus Stern Cells for Treatment of Recurrent Pterygium

Objective To evaluate the therapeutic effect of limbal corneal epithelial stem cells auto-grafting on patients with recurrent pterygium. Methods Eighty-eight cases (88 eyes) with recurrent pterygium were randomly divided into 2 groups, excision of ptergyium with limbal corneal epithelial stem cells autografting was as combine group A (44 cases,44 eyes), the other cases of primary pterygium (group B)were excised under microscope with routine microsurgical procedure. Patients were followed up for 4 to 28 months(averaged 14.30 ±7.42 months). Results There were 9 eyes(20.45%) and 3 eyes (6.82%) that recurred after the operation in two groups, the differences were significant between two groups(x2=1.137, P<0.05). Conclusion Limbal corneal epitheliat stem cells autografting was the most effective way on recurrent pterygium treatment.