不同宿主贾第虫对不同实验动物感染的比较 |
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引用本文: | 符杰 戚晨伟. 不同宿主贾第虫对不同实验动物感染的比较[J]. 实验动物与比较医学, 1996, 16(2): 75-78 |
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作者姓名: | 符杰 戚晨伟 |
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作者单位: | 中国科学院上海实验动物中心,中国科学院上海生物工程研究中心,上海实验动物研究中心 |
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摘 要: | 以来自人的兰氏贾第虫滋养体经口和直接接种于十二指肠感染不同实验动物,以来自自然感染的金黄仓鼠的西蒙氏贾第虫滋养体经口分别对大鼠、豚鼠和兔作交叉感染。结果,大鼠、豚鼠和兔对兰氏贾第虫滋养体均不感染;但西蒙氏贾第虫对大鼠具有感染力,而对豚鼠、兔无感染力。同时发现,幼龄大鼠比性成熟期大鼠易感,但滋养体在十二指肠内的分布十分相似,主要分布于前段、中前段和中段,而中后段和后段相对较少。尽管来自不同宿主的贾第虫经染色后形态相似,无法区别,但本文结果表明两者的宿主特异性存在差异。
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关 键 词: | 兰氏贾第虫 西蒙氏贾第虫 滋养体 交叉感染 实验动物 |
Crosstransmission of Trophozoites of Giardia spp. from Different Hosts to Different Laboratory Animals |
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Abstract: | The laboratory animals were challenged with trophozoites of G.lamblia from axenic culture and trophozoites of G.simoni from naturally infected golden hamsters by oral and duodenal routes.The results showed that all the animals (9 rats,9 guinea pigs and 4 rabbits) challenged with cultured trophozoites of G.lamblia were not infected, and that when challenged with G.simoni the rats ( n =10) were infected,while the guinea pigs ( n =8) and rabbits ( n =2) were not.It indicated that there was a biological difference between G.lamblia and G.simoni although they were morphologically identical.It was also observed that young rats were more susceptible than adult rats to G.simoni .The cysts of G.simoni were detected in rat faeces.It indicated that G.simoni could complete its life cycle in rats. |
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