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ER与PR在钼靶X线假阴性乳腺癌中的表达及临床意义
引用本文:葛怀娥,臧春霞,李红文,耿翠芝,白希永,崔海滨. ER与PR在钼靶X线假阴性乳腺癌中的表达及临床意义[J]. 河北医药, 2009, 31(7): 805-806
作者姓名:葛怀娥  臧春霞  李红文  耿翠芝  白希永  崔海滨
作者单位:河北省沧州市中心医院肿瘤外一科,061001;河北医科大学第四医院外一科
摘    要:目的分析ER、PR在钼靶X线假阴性乳腺癌中表达的临床意义。方法将183例女性乳腺癌按照钼靶X线结果分成阳性和假阴性2组,采用免疫组化S-P法检测其ER、PR。结果钼靶X线假阴性组中,ER阳性比率低于阳性组(40%与67.57%,P=0.003);但2组患者PR阳性表达率差异无统计学意义(62.86%与57.43%,P=0.575)。结论与钼靶X线阳性患者相比,钼靶X线假阴性患者ER阳性表达率低,提示该组患者内分泌治疗效果及预后较差。

关 键 词:钼靶X线假阴性  免疫组化  乳腺癌

Expression and clinical significance of estrogen receptor and progesterone receptor of breast cancer with false-negative mammograms
GE Huai'e,ZANG Chunxia,LI Hongwen,et al.. Expression and clinical significance of estrogen receptor and progesterone receptor of breast cancer with false-negative mammograms[J]. Hebei Medical Journal, 2009, 31(7): 805-806
Authors:GE Huai'e  ZANG Chunxia  LI Hongwen  et al.
Affiliation:GE Huai'e,ZANG Chunxia,LI Hongwen,et al.Department of Oncology,The Central Hospital of Cangzhou City,Hebei,Cangzhou 061001,China
Abstract:Objective To analyzes the clinical significance of estrogen receptor(ER) and progesterone receptor(PR) expression in patients with false-negative mammograms.Methods 183 female patients with breast cancer identified by pathology were divided into two groups,positive group and false-negative group.The Streptavidin-peroxidase(SP) method(immunohistochemistry) was used to determine ER,PR of the patients.Results The ER positive rate in false-negative group was significantly lower than that of positive group(40% v...
Keywords:false-negative mammograms  immunohistochemistry  breast cancer  
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