Properties of mouse leukemia viruses. VIII. The major viral glycoprotein of Friend leukemia virus. Seroimmunological, interfering and hemagglutinating capacities |
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Authors: | Gerhard Hunsmann Volker Moennig Liselotte Pister Eveline Seifert Werner Schäfer |
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Affiliation: | Max-Planck-Institut für Virusforschung, Tübingen, Germany |
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Abstract: | The purified major glycoprotein (GP71) of Friend leukemia virus revealed type-specific as well as species-specific and interspecies antigenicities in various types of seroimmunological tests. It was also able to induce the production of neutralizing antibodies, to interfere with murine leukemia viruses from two different serotypes, and to hemagglutinate. Demonstration of hemagglutination became possible after reconstitution of GP71 to multivalent complexes by suitable species-specific antibody (indirect hemagglutination). |
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