| 抗病毒口服液挥发油提取工艺的研究 |
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| 引用本文： | 邓丽明,林华庆,刘国宏,邓红,张蜀.抗病毒口服液挥发油提取工艺的研究[J].广东药学院学报,2007,23(2):119-120. |
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| 作者姓名： | 邓丽明 林华庆 刘国宏 邓红 张蜀 |
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| 作者单位： | 1. 广东药学院,药物研究所,广东,广州,510006
2. 广州市香雪制药股份有限公司,广东,广州,510530 |
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| 摘 要： | 目的 优选抗病毒口服液中广藿香、连翘、郁金、石菖蒲等4味药材挥发油最佳提取工艺.方法 采用水蒸气蒸馏法提取挥发油,以收油率为指标,采用正交试验设计考察药材粒径、加水倍数、浸泡时间、提取时间等因素.结果 最佳提取条件为:药材粉细段(＜10 mm),加入8倍量水,浸泡3 h,提取6 h.结论 优选得到的工艺稳定可行.
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| 关 键 词： | 广藿香 连翘 郁金 石菖蒲 挥发油 正交试验 |
| 文章编号： | 1006-8783（2007）02-0119-02 |
| 修稿时间： | 2007-03-122007-04-13 |
Optimization of the extraction procedure of essential oil from four herbs |
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| DENG Li-ming,LIN Hua-qing,LIU Guo-hong,DENG Hong,ZHANG Shu.Optimization of the extraction procedure of essential oil from four herbs[J].Academic Journal of Guangdong College of Pharmacy,2007,23(2):119-120. |
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| Authors: | DENG Li-ming LIN Hua-qing LIU Guo-hong DENG Hong ZHANG Shu |
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| Institution: | 1. Institute of Medica, Guangdong College of Pharmacy, Guangzhou, Guangdong 510006, China; 2. Guangzhou Xiangxue Pharmaceutical Factory Co. Ltd. , Guangzhou, Guangdong 510530, China |
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| Abstract: | Objective To optimize the extraction procedure of essential oils from Herba Pogostemonis,Fructus Forsythiae,Radix curcumae and Rhizoma Acori Tatarinowii,four main components of Kangbingdu oral solution.Methods The essential oil was extracted by steam distillation.Orthogonal test was used to optimize extraction yield-related factors such as the grain size of the material,quantity of water,soaking time and extraction time.Chemical constituents of the extracted essential oil were identified by TLC.Results The optimized extraction conditions were as following: 10 mm or less in grain size,8 times of water,three hours of immersion and six hours of distillation.Conclusion This optimized extraction process is stable and highly efficient. |
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| Keywords: | Herba Pogostemonis Fructus Forsythiae Radix curcumae Rhizoma Acori Tatarinowii essential oil orthogonal test |
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