| 灯盏细辛注射液对急性脑梗死患者MMP-9的影响 |
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| 引用本文： | 周治平,杨国帅,王爱岳. 灯盏细辛注射液对急性脑梗死患者MMP-9的影响[J]. 现代预防医学, 2011, 38(13): 2660-2661 |
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| 作者姓名： | 周治平 杨国帅 王爱岳 |
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| 作者单位： | 海口市人民医院神经内科,海口,570208 |
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| 摘 要： | [目的]观察灯盏细辛注射液对急性脑梗死(ACI)患者的临床疗效及对患者血清MMP-9水平的影响。[方法]81例ACI患者随机分成灯盏细辛组(n=42)和常规治疗组(n=39),以及健康对照组(n=40)。采用ELISA法检测两组患者治疗前和治疗后24h,72h,7d,14d的血清MMP-9水平,并在治疗后14d进行临床疗效的判定。[结果]治疗前两组的MMP-9水平高于健康对照组(P﹤0.05),两组治疗后MMP-9水平均明显下降,灯盏细辛组降低较常规治疗组更明显(P﹤0.05)。而且灯盏细辛组临床总有效率明显高于常规治疗组(P﹤0.05)。[结论]灯盏细辛注射液可能通过下调MMP-9的水平发挥治疗ACI的有效性。
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| 关 键 词： | 灯盏细辛 脑梗死 基质金属蛋白酶-9 |
EFFECT OF ERIGERON INJECTION ON MMP-9 IN PATIENT WITH ACUTE CEREBRAL INFRACTION |
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| ZHOU Zhi-ping,YANG Guo-shuai,WANG Ai-yue. EFFECT OF ERIGERON INJECTION ON MMP-9 IN PATIENT WITH ACUTE CEREBRAL INFRACTION[J]. Modern Preventive Medicine, 2011, 38(13): 2660-2661 |
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| Authors: | ZHOU Zhi-ping YANG Guo-shuai WANG Ai-yue |
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| Affiliation: | ZHOU Zhi-ping,YANG Guo-shuai,WANG Ai-yue.(Department of Neurology,Haikou People's Hospital,Haikou 570208,China) |
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| Abstract: | [Objective]To investigate the clinical effect of Erigeron Injection for acute cerebral infaction(ACI)and its influence on levels of matrix metalloprotenaise-9(MMP-9)in peripheral blood of patients with ACI.[Methods]81 patients with ACI were randomly divided into treated group(n = 42)and the conventional control group(n = 39).40 healthy subjects were as normal control group.Expression of MMP-9 was measured by ELISA before and after treatment of 24h,72h,7d and 14d.The clinical effect was detected after 14 day... |
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| Keywords: | Erigeron Injection Cerebral infarction Matrix metalloprotenaise-9 |
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