急性心肌梗死患者血清瘦素的改变及临床意义

[目的]观察临床急性心肌梗死(AMI)患者血清瘦素水平的变化,探讨其临床意义。[方法]随机选取临床研究对象68例,其中AMI组患者36例,正常对照组32例。所有研究对象均测定血压(Bp)、血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高敏C-反应蛋白(hs-CRP)和瘦素水平。[结果]与正常对照组比较,AMI组患者的Bp、TC、LDL-C、hs-CRP和瘦素水平均有明显升高(P﹤0.05),而两组间TG无明显差别。AMI患者的瘦素水平与hs-CRP有明显的正相关性(r=0.319,P﹤0.05)。[结论]AMI患者瘦素水平明显升高,提示它可能是一种重要的损伤因子,在AMI的发病中起重要作用。

THE CHANGE OF LEPTIN IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

[Objective]To observe the change of serum level of leptin in patients with acute myocardial infarction(AMI)and explore its clinical significance.[Methods]68 subjects were randomly selected to AMI group(n = 36)and control group(n = 32).Blood pressure(BP),triglycerides(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),high sensetivity C-reactive protein(hs-CRP)and leptin were measured in all subjects.[Results]Compared to those in the control group,BP,TC,LDL-C,hs-CRP and leptin in the AMI gr...