急性冠脉综合征介入术前应用他汀类药物强化治疗的影响及效果观察

目的]观察急性冠脉综合征介入术前应用他汀类药物强化治疗的影响及效果。方法]选择56例急性冠脉综合征患者,随机将其分为2组,强化组和常规组,两组术前10d给予阿伐他汀20mg口服,强化组手术当日给予阿伐他丁80mg,常规组则仍给予20mg,术后两组继续应用阿伐他丁20mg。测定术前及术后1d,5d及10d血清中C反应蛋白及血脂水平。结果]2组患者间术后血脂均未见明显变化,2组间相比及2组与术前相比差异均无统计学意义。强化组术后1d、5d、10d其C反应蛋白均较常规组低(P﹤0.05)。结论]他丁类药物不仅有降脂作用,其抗炎作用也是很明显的。

OBSERVATION OF THE IMPACT AND EFFECT OF THE INTERVENTION ON ACUTE CORONARY SYNDROME WITH PREOPERATIVE ENHANCED STATIN DRUG

Objective]To observe the impact and effect of the intervention of acute coronary syndrome with preoperative enhanced statin drug.Methods]56 patients with acute coronary syndrome were randomly divided into strengthened group and the conventional group,all were given to oral administration of atorvastatin 20mg every day since 10 days before intervention,but 80mg for strengthened group and 20mg still for controlled group on operative day,after that,all were still given to 20mg as the original.C-reactive prot...