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A case of postoperative liver metastasis from gastric cancer which responded well to weekly chemotherapy with paclitaxel
Authors:Yamamoto Daigo  Hamada Yoshinori  Yamamoto Chizuko  Inoue Kentaro  Yamamoto Mitsuo
Affiliation:Dept. of Surgery, Seiko Hospital.
Abstract:We report a case of postoperative liver metastasis from gastric cancer showing a remarkable response to weekly administration of paclitaxel (TXL). The patient was a 50-year-old woman who underwent total gastrectomy. One month later, liver metastasis and a small amount of ascites were detected by CT scan. Therefore, the patient was administered weekly TXL. TXL (80 mg/m2) was infused over 1 hour after short premedication on an outpatient basis. Administration was continued for 3 weeks followed by 1 week rest. Liver metastasis and ascites disappeared 3 months after administration. The toxic events were leukopenia (grade 1) and alopecia (grade 1). No major adverse effects were observed.
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