| 工艺参数对雷贝拉唑钠肠溶片体外释放度的影响 |
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| 引用本文： | 高原,李玉柱,刘珏,王小琳,陈彬华. 工艺参数对雷贝拉唑钠肠溶片体外释放度的影响[J]. 中国医药工业杂志, 2009, 40(10) |
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| 作者姓名： | 高原 李玉柱 刘珏 王小琳 陈彬华 |
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| 作者单位： | 信谊药厂药物研发中心,上海,201206 |
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| 摘 要： | 考察各工艺因素(制粒、压片、包衣参数)对雷贝拉唑钠肠溶片释放度的影响.按优化处方制得的样品与市售"波利特"的体外释放无明显差异.
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| 关 键 词： | 工艺参数 包衣 体外释放度 贝拉唑钠 |
Effects of In-process Parameters on in vitro Release of Sodium Rabeprazole Enteric-coated Tablets |
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| Abstract: | The effects of the in-process parameters of granulation,compression and coating on in vitro release of sodium rabeprazole enteric-coated tablets were investigated.There was no signifi cant difference between the release of products prepared by optimized formulation and the imported product Pariet. |
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| Keywords: | in-process parameter enteric-coated in vitro release sodium rabeprazole |
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