裸花紫珠的脂溶性化学成分

目的 研究裸花紫珠(Callicarpa nudiflora Hook. Et Arn.)叶的脂溶性化学成分。方法 采用硅胶柱色谱、Sephadex LH-20柱色谱和大孔树脂HPD-100柱色谱分离化合物，通过理化性质和波谱分析确定化合物的结构。结果 从裸花紫珠叶的水提取物中分离得到8个已知化合物，分别鉴定为：5,4′-二羟基-3,7,3′-三甲氧基黄酮（1）、5-羟基-3,7,3′,4′-四甲氧基黄酮（2）、木犀草素（3）、木犀草素-7-O-β-D-吡喃葡萄糖苷（4）、七叶內酯（5）、乌苏-12-烯-3β-醇（6）、熊果酸（7）、β-谷甾醇（8）。结论 化合物5、6为首次从紫珠属植物中分离得到；化合物1~3、8为首次从该植物中分离得到；香豆素类化合物为首次从紫珠属植物中分得的化合物类型。

Lipophilic compounds of Callicarpa nudiflora Hook. Et Arn.

Aim To study the lipophilic compounds of the leaves of Callicarpa nudiflora Hook. Et Arn. Methods This compounds were isolated by column chromatography on silica gel, Sephadex LH-20 and HPD-100 macroporous resin, and their structures were identified by physicochemical and spectral data. Results Eight compounds were obtained and identified as 5,4′-dihydroxy-3,7,3′-trimethoxyflavone (1), 5-hydroxy-3,7,3′,4′-tetramethoxyflavone (2), luteolin (3), luteolin-7-O-β-D-glucopyranoside (4), aesculetin (5), urs-12-en-3β-ol (6), ursolic acid (7), β-sitosterol (8). Conclusions Compounds 5, 6 were isolated from Callicarpa genus for the first time. Compounds 1-3, 8 were isolated from this plant for the first time. The coumarins was firstly obtained from the genus.