| 黄芪扶正汤对免疫抑制小鼠的免疫调节功能 |
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| 引用本文： | 罗晓丽,杨侃,孙明.黄芪扶正汤对免疫抑制小鼠的免疫调节功能[J].中南大学学报(医学版),2009,34(6):555-558. |
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| 作者姓名： | 罗晓丽 杨侃 孙明 |
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| 作者单位： | 中南大学1.湘雅三医院心内科， 长沙 410013； 2.湘雅医院心内科，长沙 410008 |
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| 摘 要： | 目的：探讨黄芪扶正汤对免疫抑制小鼠免疫功能的影响。方法：以氢化可的松造成免疫低下小鼠模型，用黄芪扶正汤和玉屏风散水煮液进行灌胃，检测小鼠血清溶血素的生成、IL-2和INF-γ的含量以及外周血淋巴细胞CD3+，CD4+和CD8+的表达。结果：黄芪扶正汤能明显提高免疫抑制小鼠的血清溶血素、IL-2和INF-γ的水平，提高CD4+和CD8+的比值，效果比玉屏风散更显著。结论：黄芪扶正汤对免疫抑制小鼠的免疫功能有正调节作用。
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| 关 键 词： | 黄芪扶正汤 免疫调节 T细胞亚群 |
| 收稿时间： | 2008-8-7 |
Immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice |
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| LUO Xiaoli,YANG Kan,SUN Ming.Immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2009,34(6):555-558. |
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| Authors: | LUO Xiaoli YANG Kan SUN Ming |
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| Institution: | 1.Department of Cardiology, Third Xiangya Hospital, Changsha 410013;
2.Department of Cardiology, Xiangya Hospital, Central South University, Changsha 410008, China |
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| Abstract: | ObjectiveTo explore the immunoregulatory effect of Huangqi Fuzhengtang on immunosuppressive mice.MethodsThe immunosuppressive mouse model was established by using hydrocortisone. Huangqi Fuzhengtang and Yupingfeng San apozema were given to the mice intragastrically. The contents of hemolysin, IL-2, and INF-γ in the mouse serum and the expression of CD3+, CD4+, and CD8+ in the peripheral blood lymphocytes were measured. ResultsHuangqi Fuzhengtang could obviously elevate the contents of hemolysin, IL-2, INF-γ and the ratio of CD4+ and CD8+, which was more effective than Yupingfeng San. ConclusionHuangqi Fuzhengtang could improve the immune function in the immunosuppressive mice. |
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| Keywords: | Huangqi Fuzhengtang immunoregulation subgroup of T cells |
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