胃原发性上皮样血管肉瘤1例报道并文献复习

目的探讨胃上皮样血管肉瘤的临床病理特征、治疗及预后。方法对1例原发于胃的上皮样血管肉瘤进行组织形态学、免疫组织化学分析，并复习相关文献。结果临床表现及大体病理无特征性；镜下瘤细胞呈上皮样特征，异型性明显，表达CD31、CD34、Vim。结合文献，消化道原发性上皮样血管肉瘤男性多于女性，平均发病年龄为60．4岁。结论消化道上皮样血管肉瘤是一种罕见的高度恶性肿瘤，术前确诊困难，预后差，转移率高，平均生存时间为7个月，主要与上皮样血管内皮瘤、恶性黑色素瘤、转移癌等鉴别。

Primary epithelioid angiosarcoma of stomach: a case report and review of literature

Objectives To study the clinical manifestation, pathological characteristics and therapeutic prognosis of epithelioid angiosarcoma (EA) in stomach. Methods A patient with primary gastric EA was analyzed with histological and immunohistochemical staining and review of the related literature. Results There were no characteristics of clinical manifestation and gross morphology in the tumor. The tumor cells presented epithelioid features with obvious atypia and expressed CD31, CD34 and vimentin. The incidence of EA in the digestive tract of male was higher than that in female. Average age of the patients was 60.4 in the literature. Conclusions EA occurred in the digestive tract is a rare malignant tumor with diagnostic difficulty, poor-prognosis and high metastatic rate. Its survival time is about 7 months. It should be differentiated from epithelioid angioendothelioma, malignant melanoma and other metastatic tumors.