磁共振扩散张量成像在中枢神经系统临床应用

扩散张量成像(diffusion tensor imaging,DTI)可用于评估各向同性及各向异性扩散,应用各向异性分数(fractional anisotropy,FA)图可以特异性地评估白质纤维,主要用于对影响脑白质尤其是白质纤维束完整性的疾病的诊断。在常规磁共振成像显示正常时,通过分析FA图即可发现白质损伤早期的细微病理改变。在诊断多发性硬化、阿尔茨海默病、感染以及癫痫持续状态等多种中枢神经系统疾病方面具有一定的诊断价值。对肿瘤鉴别和治疗后随访有辅助作用并可清楚显示肿瘤与周围白质纤维的解剖关系,指导临床制订手术方案。文章对DTI在中枢神经系统中的临床应用现状进行综述。

Clinical Applications of MR Diffusion Tensor Imaging in Central Nervous System

DTI(Diffusion tensor imaging)can be used to evaluate isotropic and anisotropic diffusion and its fractional anisotropy map can specificly evaluate white matter.SO it is mainly used in the diagnosis of diseases related to brain white matter,especially diseases related to the integrity of white matter.We can find some tiny pathological abnormalities in early stage by fractional anisotropy map while these pathological changes can not be found by normal appearance on routine MR images.DTI has special value in t...