| 尿mAlb／Cr、NAG检测对早期糖尿病肾病的临床意义 |
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| 引用本文： | 张磊,邓君,李蓬秋,包明晶. 尿mAlb／Cr、NAG检测对早期糖尿病肾病的临床意义[J]. 内蒙古中医药, 2011, 30(13): 119-120 |
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| 作者姓名： | 张磊 邓君 李蓬秋 包明晶 |
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| 作者单位： | 四川省人民医院,610072 |
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| 摘 要： | 目的：研究糖尿病患者的尿液微量白蛋白，肌酐（mAlb，Cr）、N-乙酰-β—D氨基葡萄糖苷酶（NAG）与早期糖尿病肾病（DN）的诊断价值关系。方法：将149例糖尿病患者分为两组：糖尿病无肾病组与早期糖尿病肾病组，采用免疫比浊法测定尿微量白蛋白／肌酐，采用速率法检测尿NAG值，并与32例健康对照组比较。结果：糖尿病肾病患者尿mAlb／Cr、NAG明显高于对照组（P〈0．05），且尿微量白蛋白，肌酐与NAG成正相关（r=0．625，r=0．510，P〈0．05）。结论：检测尿mAlb／Cr、NAG有助于尿蛋白阴性的糖尿病肾病的早期诊断。
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| 关 键 词： | 糖尿病肾病 微白蛋白肌酐比值（mAlb Cr） NAG 临床意义 |
Clinical value of urine mAlb/Cr and NAG for early diabetic nephropathy |
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| Affiliation: | ZHANG Lei,CHEN Shu,DENG Jun,et al. The People’s Hospital of Sichuan,Chengdu,Sichuan 610072,China |
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| Abstract: | Objective To investigate the value relationship of urine mAlb/Cr and N-acety-β-D-glucosaminidase （NAG） for early diagnose of early diabetic nephropathy （DN）. Methods Urinealbumin was detected by immunity turbiktimctric method. NAG was detected by rate assay . They were detectedin 149 cases of diabetics who were DN or non-DN and 32 normal persons. Results The levels of Urine mAlb/Cr and urine NAG were obviously higher than those in controls （P〈0.05）. The urine mAlb/Cr and NAG showed positive correlation （r =0.925, r =0.810, P 〈 0.05）. Conclusion The detection of urine mAlb/Cr and NAG with urinary albumen negative is conducive to the early diagnosis of DN. |
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| Keywords: | NAG |
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