前列地尔联合云南白药治疗咯血临床观察

目的观察前列地尔联合云南白药与传统方法治疗肺部疾病所致咯血的临床效果。方法将咯血患者随机分为前列地尔联合云南白药治疗组(简称联合治疗组)和垂体后叶素联合维生素K1治疗组(简称常规治疗组)。联合治疗组48例,采用前列地尔微量泵泵入20μg每日1次,同时口服云南白药每次0.5g,每日3次;常规治疗组35例,采用常规的垂体后叶素12U入液静脉滴注每日1次,联合维生素K110mg入液静脉滴注每日1次。结果联合治疗组治疗少量咯血的有效率为100%,常规治疗组为63.64%,两组差异有统计学意义(P<0.05),联合治疗组明显优于常规治疗组。联合治疗组治疗中量咯血的有效率为80.0%,常规治疗组为71.42%,两组差异无统计学意义(P>0.05)。联合治疗组治疗大量咯血的有效率为83.33%,常规治疗组为57.14%,两组差异无统计学意义(P>0.05)。结论前列地尔联合云南白药对于少量咯血的治疗效果优于常规方法,在中量及大量咯血与常规治疗方法效果相当。但因其副作用发生少,且无绝对禁忌证,应用范围广,故为有效的治疗咯血的药物。

Clinical Effect of Alprostadil and Yunnan Baiyao for Emptysis

Objective To investigate the clinical effect of Alprostadil and Yunnan Baiyao for emptysis caused by various lung diseases.Methods 48 patients with emptysis were recruited and treated with Alprostadil and Yunnan Baiyao simultaneously;35 patients were treated with Pituitrin and Vitamin K1.Results The effective rate for mild emptysis was 100% in the Alprostadil and Yunnan Baiyao group,63.64% in the traditionally treated group.The two groups showed significant difference(P<0.05).The effective rate for moderate...