Validation of human papillomavirus genotyping by signature DNA sequence analysis |
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| Authors: | Sin Hang Lee Veronica S Vigliotti Jessica S Vigliotti Suri Pappu |
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| Institution: | (1) Department of Pathology, Milford Hospital, Milford, Connecticut, USA |
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| Abstract: | Background Screening with combined cytologic and HPV testing has led to the highest number of excessive colposcopic referrals due to
high false positive rates of the current HPV testing in the USA. How best to capitalize on the enhanced sensitivity of HPV
DNA testing while minimizing false-positive results from its lower specificity is an important task for the clinical pathologists. |
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