| 地尔硫对高血压病左室肥大及心功能的疗效优于复方降压片 |
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| 引用本文： | 贾连旺,张金良.地尔硫对高血压病左室肥大及心功能的疗效优于复方降压片[J].中国新药与临床杂志,1998(6). |
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| 作者姓名： | 贾连旺 张金良 |
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| 作者单位： | 金华市中心医院心内科(贾连旺)，金华卫生学校临床检验室(张金良) |
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| 摘 要： | 目的：比较地尔硫与复方降压片对高血压病左室肥大（ＬＶＨ）及心功能的影响。方法：高血压病伴ＬＶＨ７１例，随机单盲法分为２组。地尔硫组３６例，给地尔硫片６０ｍｇ，ｐｏ，ｔｉｄ×４８ｗｋ；对照组用复方降压片２片，ｐｏ，ｔｉｄ×４８ｗｋ。以多普勒超声心动图评定ＬＶＨ与心功能的变化。结果：２组血压均显著下降（Ｐ＜０．０１），组间比较，Ｐ＞０．０５；地尔硫组ＬＶＨ、左室舒张功能及血液流变学各指标均有显著改善（Ｐ＜０．０１），对照组无上述效应，组间比较，Ｐ＜０．０１。结论：地尔硫对高血压病左室肥厚及心功能的疗效优于复方降压片。
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| 关 键 词： | 高血压 左心室肥大 心脏功能试验 血液流变学 |
Diltiazem is better than Fu_fang Jiang_ya Pian in treating left ventricular hypertrophy and heart function of essential hypertension |
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| JIA Lian_Wang.Diltiazem is better than Fu_fang Jiang_ya Pian in treating left ventricular hypertrophy and heart function of essential hypertension[J].Chinese Journal of New Drugs and Clinical Remedies,1998(6). |
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| Authors: | JIA Lian_Wang |
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| Abstract: | AIM: To compare the effects of diltiazem (Dil) and Fu_fang Jiang_ya Pian on left ventricular hypertrophy (LVH) and heart function of essential hypertension. METHODS: Seventy_one patients with LVH of essential hypertension were randomly divided into two groups: one group (36 patients) was treated with Dil tablet 60 mg, po, tid for 48 wk; the other group (35 patients) was given Fu_fang Jiang_ya Pian 2 tablets, po, tid for 48 wk. The changes of LVH and heart function were determined by Doppler echocardiography. RESULTS: The blood pressure of the two groups decreased (P<0.01). The LVH, left ventricular diastolic function, and hemorheology in Dil group were significantly improved, but in Fu_fang Jiang_ya Pian group there was no effect ( P < 0.01). CONCLUSION: Dil is better than Fu_fang Jiang_ya Pian. |
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| Keywords: | diltiazem hypertension left ventricular hypertrophy heart function tests hemorheology |
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