Increased radiographic damage scores at the onset of seropositive rheumatoid arthritis in older patients are associated with osteoarthritis of the hands, but not with more rapid progression of damage |
| |
| Authors: | Khanna Dinesh Ranganath Veena K Fitzgerald John Park Grace S Altman Roy D Elashoff David Gold Richard H Sharp John T Furst Daniel E Paulus Harold E;Western Consortium of Practicing Rheumatologists |
| |
| Institution: | University of California at Los Angeles, USA. dinesh.khanna@uc.edu |
| |
| Abstract: | OBJECTIVE: To investigate the impact of patient age at symptom onset on radiographic joint damage at study entry, and on subsequent progression of damage in a cohort of patients with early seropositive rheumatoid arthritis (RA). METHODS: We studied 186 patients with RA of <15 months' duration. All patients had active disease and had not received disease-modifying antirheumatic drugs. At study entry and during followup, total Sharp scores (TSS), RA-associated joint space narrowing (RA-JSN), and erosions were determined on hand and foot radiographs. Baseline radiographs were also scored for osteoarthritis (OA)-related JSN (OA-JSN) and osteophytes. Older patients (>55 years) and younger patients (
|
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
