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骨髓组织印片细胞学检查的诊断价值
引用本文:吕萍,朱蕾,龚旭波,卢兴国.骨髓组织印片细胞学检查的诊断价值[J].苏州大学学报(自然科学版),2008,28(3).
作者姓名:吕萍  朱蕾  龚旭波  卢兴国
作者单位:[1]浙江省监狱中心医院检验科,浙江杭州310016 [2]浙江大学附属第二医院血液科,浙江杭州310009
摘    要:目的 研究骨髓组织印片(简称印片)细胞学检查的应用价值.方法 自患者髂后上棘抽吸骨髓后,用骨髓活检针以环钻二步法将获取的骨髓组织(长度0.6 cm以上)置于载玻片上,均匀滚动制成印片272张,以同步采集的骨髓涂片(简称涂片)和骨髓切片(简称切片)为对照,进行细胞学检查.结果 印片有核细胞量明显高于涂片,差异有统计学意义(P<0.01),而与切片的差异则无统计学意义(P<0.05);印片细胞数减少者涂片大多减少,反之差异明显;以切片为金标准,印片诊断性能指标和Youden指数优于涂片;印片还可大体观察肿瘤细胞的组织形态(浸润结构).结论 印片评估有核细胞有明显的长处,也可初步了解组织形态学概况,同涂片快速检查互补,可明显提高涂片的细胞学诊断水平,可作为常规项目应用.

关 键 词:骨髓组织印片  应用价值  骨髓涂片  骨髓切片  骨髓组织  印片细胞学检查  诊断价值  Biopsy  Bone  Marrow  Examination  Cytology  Application  常规项目  水平  细胞学诊断  互补  快速检查  组织形态学  评估  结构  浸润  肿瘤细胞  指数  性能指标

The Clincal Application in Cytology Examination of Bone Marrow Biopsy Imprints
LV Ping,ZHU Lei,GONG Xu-bo,LU Xing-guo.The Clincal Application in Cytology Examination of Bone Marrow Biopsy Imprints[J].Suzhou University Journal of Medical Science,2008,28(3).
Authors:LV Ping  ZHU Lei  GONG Xu-bo  LU Xing-guo
Institution:LV Ping1,ZHU Lei2,GONG Xu-bo2,LU Xing-guo2(1.Clinical Laboratory,Zhejiang Province Prison Central Hospital,Zhejiang Hangzhou 310016,China,2.Dept of Haematology,the Second Hospital Affiliated to Zhejiang University,Zhejiang Hangzhou 310009,China)
Abstract:Objective To study the application value in bone marrow biopsy imprint(called imprint for short).Methods After the 272 patients' marrow aspirates were obtained through the posterior superior iliac spine,the marrow tissue(length usually than 0.6 cm) which was obtained by trephine biopsy was put on the slides to make the imprints(the tissues were fixed in Bouin's liquid) and the imprints cytology examination was carried out compared with the marrow smears and sections.Results The cellularity in imprints was s...
Keywords:bone marrow biopsy imprints  application value  bone marrow smears  bone marrow sections  
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