| 峨参提取物对肺癌细胞A549和H460增殖的抑制作用初步观察 |
| |
| 引用本文： | 涂显琴,马超英,徐寅生,高雅蓉,牛顺子,唐静,耿耘,蒋合众. 峨参提取物对肺癌细胞A549和H460增殖的抑制作用初步观察[J]. 中华中医药学刊, 2012, 0(1): 60-62 |
| |
| 作者姓名： | 涂显琴 马超英 徐寅生 高雅蓉 牛顺子 唐静 耿耘 蒋合众 |
| |
| 作者单位： | 西南交通大学生命科学与工程学院;石药集团恩必普药业有限公司 |
| |
| 基金项目： | 国家自然科学基金资助项目(81073036);中央高校基本科研业务费专项研究资助项目(SWJTU09ZT29) |
| |
| 摘 要： | 目的:观察峨参石油醚、氯仿、乙酸乙酯和正丁醇部位提取物对肺癌细胞A549和H460增殖的抑制作用。方法:应用MTT比色法检测不同部位、不同浓度峨参提取物对肺癌细胞A549和H460增殖的抑制作用。结果:10～1000μg/mL的4个部位峨参提取物对体外培养的人肺癌细胞A549和H460的增殖具有抑制作用,其中石油醚部位、氯仿部位和乙酸乙酯部位提取物抑制作用更明显。结论:峨参不同部位提取物对肺癌细胞增殖具有明显的抑制作用。
|
| 关 键 词： | 峨参提取物 肺癌细胞 细胞凋亡 |
Tentative Study of Anthriscus Extracts Repressing the Proliferation of Lung Cancer Cell A549 and H460 |
| |
| TU Xian-qin,MA Chao-ying,XU Yin-sheng,GAO Ya-rong,NIU Shun-zi,TANG Jing,GENG Yun,JIANG He-zhong. Tentative Study of Anthriscus Extracts Repressing the Proliferation of Lung Cancer Cell A549 and H460[J]. Chinese Archives of Traditional Chinese Medicine, 2012, 0(1): 60-62 |
| |
| Authors: | TU Xian-qin MA Chao-ying XU Yin-sheng GAO Ya-rong NIU Shun-zi TANG Jing GENG Yun JIANG He-zhong |
| |
| Affiliation: | 1(1.Southwest Jiaotong University,Chengdu 610031,Sichuan,China; 2.Shijiazhuang Pharmaceutical Group NBP Pharmaceutical Co.,Ltd.,Shijiazhuang 100036,Hebei,China) |
| |
| Abstract: | Objective:To observe the inhibition of petroleum ether,chloroform,ethyl acetate and butanol extracts of Anthriscus sylvestris(L.)Hoffm on the proliferation of lung cancer cell A549 and H460.Methods:To detect the inhibition effects of different parts with different concentrations Anthriscus extracts on the proliferation of lung cancer cell A549 and H460 by MTT assay.Result:4 parts of Anthriscus sylvestris extracts have inhibition effect on the proliferation of lung cancer cell A549 and H460 when concentrations are from 10 to 1000μg/mL,moreover,the extracts of petroleum ether,chloroform and ethyl acetate parts have more obvious evident inhibition.Conclusion:The extracts of different parts of Anthriscus have evident inhibition effect on the proliferation of lung cancer cell. |
| |
| Keywords: | extracts of Anthriscus lung cancer cell Apoptosis |
| 本文献已被 CNKI 等数据库收录！ |
|
