分离性焦虑障碍史与成年期精神疾病的关系(综述)

本文对早期分离性焦虑障碍史与成年期精神疾病两者关系的国外研究文献进行了综述。分析表明:分离性焦虑障碍史与成年期多种精神疾病之间存在关联,纵向研究结果支持分离性焦虑障碍史作为成年期焦虑障碍谱系及抑郁的风险因素,但其是否作为成年期心境恶劣、双相情感障碍、人格障碍、进食障碍的风险因素还需纵向研究的确认。此外,在儿童期,分离性焦虑障碍与性别认同障碍存在共患关系,可能对个体性心理发展产生影响。现有研究中存在的不足是,在检验分离性焦虑障碍史与成年期精神疾病两者关系时,未见有对遗传和环境变量的控制,也少见有对共病进行控制,而这类控制对确认其是否作为风险及风险大小是十分必要的。

Relationship between medical history of separation anxiety disorder in early life and mental diseases in adulthood(Review)

This paper reviewed the literatures from the bibliographic database PubMed on the relation between separation anxiety disorder(SAD) in early life and mental diseases in adulthood.The data indicated that SAD was related to several different mental diseases in adulthood.The longitudinal designed studies supported that SAD served as a risk for adult anxiety disorders spectrum or depression.However,whether SAD is a risk for dysthymic,bipolar,personality and eating disorder in adulthood was uncertainty,so further studies based on longitudinal design are needed.It was also found that SAD usually comorbid with gender identity disorder in childhood,and such comorbidity might influence individual psychosexual development.The limitation among these literatures was,when the relation between SAD and mental disease in adulthood was examined,the effect caused by genetic and environmental variables or comorbidity variables was uncontrolled,and such control was crucial for the study to determine whether SAD served as a risk or how high of the risk rate contributed by SAD.