| 轻度认知障碍患者血清生化指标与认知损伤关系 |
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| 引用本文： | 张丽,任小垌,肖彤彤,蔡思捷,朱海林,程静. 轻度认知障碍患者血清生化指标与认知损伤关系[J]. 公共卫生与预防医学, 2019, 30(4): 86-89 |
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| 作者姓名： | 张丽 任小垌 肖彤彤 蔡思捷 朱海林 程静 |
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| 作者单位： | 湖北省中西医结合医院神经内科,武汉,430074;武汉科技大学医学院公共卫生学院营养与食品卫生学系;职业危害识别与控制湖北省重点实验室;武汉科技大学医学院公共卫生学院营养与食品卫生学系;职业危害识别与控制湖北省重点实验室;武汉东湖新技术开发区疾病预防控制中心 |
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| 基金项目： | 中国营养学会科研基金;国家级大学生创新创业训练计划项目;湖北高校省级大学生创新创业训练计划项目 |
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| 摘 要： | 目的探讨轻度认知障碍(MCI)患者血清生化检测指标与认知损伤的关系。方法检测119MCI患者与232例认知正常人的血清生化指标,应用自制的危险因素调查表调查所有研究对象。采用病例对照的实验设计,通过计算相关指标的χ2值及P值,对MCI的危险因素进行多因素Logistic回归分析。结果单因素分析显示文化程度、饮酒、社交活动和谷氨酰转移酶差异有统计学意义(P<0.05),多因素Logistic回归分析显示,较高的谷氨酰转移酶水平(OR=0.966,95%CI:0.936~0.998)和较高的文化程度是认知保护因素。结论较高的血清谷氨酰转移酶水平可能是MCI的保护因素,但该结论还需要更多研究证实。
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| 关 键 词： | 轻度认知障碍 血清 生化指标 谷氨酰转移酶 |
Relationship between serum biochemical indices and cognitive impairment in patients with mild cognitive impairment |
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| ZHANG Li,REN Xiaotong,XIAO Tongtong,CAI Sijie,ZHU Hailin,CHENG Jing. Relationship between serum biochemical indices and cognitive impairment in patients with mild cognitive impairment[J]. Journal of Public Health and Preventive Medicine, 2019, 30(4): 86-89 |
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| Authors: | ZHANG Li REN Xiaotong XIAO Tongtong CAI Sijie ZHU Hailin CHENG Jing |
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| Affiliation: | (Department of Neurolog,Hubei Provincia Hospital of Integrated Chinese & Western Medicine,Wuhan 430074,China;Department of Nutrition and Food Hygiene,School of Public Health,Wuhan University of Science and Technology, Wuhan 430074,China;Hubei Province Key Laboratory of Occupational Hazard Identification and Control,Wuhan University of Science and Technology, Wuhan 430074,China;Public Health Service Center of Wuhan East Lake High-tech Development Zone,Wuhan 430075,China) |
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| Abstract: | ZHANG Li;REN Xiaotong;XIAO Tongtong;CAI Sijie;ZHU Hailin;CHENG Jing(Department of Neurolog,Hubei Provincia Hospital of Integrated Chinese & Western Medicine,Wuhan 430074,China;Department of Nutrition and Food Hygiene,School of Public Health,Wuhan University of Science and Technology, Wuhan 430074,China;Hubei Province Key Laboratory of Occupational Hazard Identification and Control,Wuhan University of Science and Technology, Wuhan 430074,China;Public Health Service Center of Wuhan East Lake High-tech Development Zone,Wuhan 430075,China) |
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| Keywords: | Mild cognitive impairment Serum Biochemical parameters Glutamyl transferase |
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