Oxygenated cembranoids from a Formosan soft coral Sinularia gibberosa |
| |
| Authors: | Ahmed Atallah F Wen Zhi-Hong Su Jui-Hsin Hsieh Ya-Ting Wu Yang-Chang Hu Wan-Ping Sheu Jyh-Horng |
| |
| Affiliation: | Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan, Replublic of China. |
| |
| Abstract: | Chemical investigation of a Formosan soft coral, Sinularia gibberosa, has led to the isolation of eight oxygenated cembranoids, 1- 8, including seven new compounds, gibberosenes A-G ( 2- 8). None of these compounds were found to be cytotoxic toward a limited panel of cancer cell lines. Compound 1 significantly inhibited the accumulation of the pro-inflammatory COX-2 protein of the LPS-stimulated RAW264.7 macrophage cells. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
