原发性膀胱淀粉样变(附4例报告)

目的：探讨原发性膀胱淀粉样变的诊治方法。方法：回顾性分析4例原发性膀胱淀粉样变的临床资料。结果：3例行电切或开放手术后辅以二甲基亚砜(DMSO)膀胱灌注，随访3～6年未见复发。1例单纯DMSO膀胱灌注，2年后复发。结论：原发性膀胱淀粉样变极易与膀胱癌混淆，需经病理及特殊染色确诊。治疗上尽可能切除病变组织，术后辅以DMSO膀胱灌注。

Primary amyloidosis of the bladder

Objective:To detect the diagnostic and therapic methods of primary amyloidosis of the bladder.Method:Reviewed 4 cases of primary amyloidosis of the bladder in our hospital.Result:Three patients received TRUBT or operation associated with DMSO instillation, none recurrence was found at the 3 year follow up.One patient received DMSO instillation and the disorder was recurred in two years.Conclusion:Primary localized bladder amyloidosis may be clinically as well as cystoscopically indistinguishable from transitional cell carcinoma. Definitive diagnosis rests on histopathologic examination of a biopsy specimen and special staining. The rules of the treatments include resecting the lesions as more as possible. DMSO bladder instillation is helpful. Annual cystoscopy follow-up should be made.