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急性呼吸困难的病因分析和血浆N末端B型利钠肽原检测的应用价值
引用本文:魏敦双. 急性呼吸困难的病因分析和血浆N末端B型利钠肽原检测的应用价值[J]. 临床肺科杂志, 2011, 16(8): 1236-1238
作者姓名:魏敦双
作者单位:武汉,湖北省中山医院急诊科,湖北,430022
摘    要:目的分析急性呼吸困难的病因,探讨检测血浆N末端B利钠肽原(NT-proBNP)对急性呼吸困难中充血性心力衰竭的诊断价值。方法分析211例急性呼吸困难患者的临床资料,将患者分为充血性心力衰竭组和非充血性心力衰竭组。比较两组患者血浆NT-proBNP水平。结果 211例急性呼吸困难患者中,充血性心力衰竭的发生率96例(45.5%)。充血性心力衰竭患者血浆NT-proBNP水平[3947.6 pg/m l,1421.1~11378.3 pg/m l]显著高于非充血性心力衰竭患者[412.4 pg/m l,41.2-1123.2 pg/m l](P〈0.01)。以血浆NT-proBNP水平≥800 pg/m l为判别标准与非充血性心力衰竭鉴别,诊断充血性心力衰竭的敏感性、特异性和准确性分别为83.3%、82.6%和82.9%。结果充血性心力衰竭是急性呼吸困难的最常见原因;检测血浆NT-proBNP水平有助于充血性心力衰竭的诊断。

关 键 词:呼吸困难  N末端B型利钠肽原  充血性心力衰竭

Etiology of acute dyspnea and use of N-terminal pro brain natriuretic peptide blood level in differential diagnosis
WEI Dun-shuang. Etiology of acute dyspnea and use of N-terminal pro brain natriuretic peptide blood level in differential diagnosis[J]. Journal of Clinical Pulmonary Medicine, 2011, 16(8): 1236-1238
Authors:WEI Dun-shuang
Affiliation:WEI Dun-shuang Department of Emergency,Hubei Zhongshan Hospital,Wuhan 430030,China
Abstract:Objective To investigate etiology of acute dyspnea and use of N-terminal pro brain natriuretic peptide(NT-proBNP) blood level in differential diagnosis.Methods 211 patients with dyspnea were divided into congestive heart failure(CHF) group and non-congestive heart failure(non-CHF) group through analysis of their clinical data.NT-proBNP blood level was compared between the two groups.Results In 211 patients with dyspnea,incidence of CHF was 45.5%.NT-proBNP blood level in patients with CHF was higher than tha...
Keywords:Dyspnea  N-terminal pro brain natriuretic peptide  congestive heart failure  
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