| 2004～2009年我中心结核分枝杆菌临床株耐药趋势 |
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| 引用本文： | 廖传玉,黄正谷,陈天刚,李同心,万东勇,饶霞,徐艳,侯毅,钟敏,严哓峰.2004～2009年我中心结核分枝杆菌临床株耐药趋势[J].临床肺科杂志,2011,16(8):1212-1213. |
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| 作者姓名： | 廖传玉 黄正谷 陈天刚 李同心 万东勇 饶霞 徐艳 侯毅 钟敏 严哓峰 |
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| 作者单位： | 重庆市公共卫生医疗救治中心暨重庆市结核病治疗中心,重庆,400036 |
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| 基金项目： | 重庆市卫生局医学科研重点项目 |
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| 摘 要： | 目的探讨重庆市公共卫生医疗救治中心临床结核菌株耐药趋势。方法采用BACT/ALERT3D进行各种临床标本的分枝杆菌分离培养,L-J绝对浓度间接法进行分枝杆菌的初步菌种鉴定和药物敏感试验。结果 1916株结核分枝杆菌在11种药敏结果中耐一种药物的耐药率为62.8%（1204株）,耐多药（MDR）24.1%（462株）,广泛耐药（XDR）4.0%（76株）。结论重庆市公共卫生医疗救治中心就诊的结核病患者结核分枝杆菌株的总耐药率、MDR和XDR等明显高于全国结核病耐药性基线调查结果,其高耐药趋势与该中心收治基层和周边地区转送难复治结核较多有较密切关系。
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| 关 键 词： | 结核分枝杆菌 耐药率 MDRXDR |
Drug resistance of clinical mycobacterium tuberculosis during 2004~2009 |
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| LIAO Chuan-yu,HUANG Zheng-gu,CHEN Tiang-ang,LI Tong-xin,WAN Dong-yong,RAO Xia,XU Yan,HOU Yi,ZHONG Min,YAN Xiao-feng.Drug resistance of clinical mycobacterium tuberculosis during 2004~2009[J].Journal of Clinical Pulmonary Medicine,2011,16(8):1212-1213. |
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| Authors: | LIAO Chuan-yu HUANG Zheng-gu CHEN Tiang-ang LI Tong-xin WAN Dong-yong RAO Xia XU Yan HOU Yi ZHONG Min YAN Xiao-feng |
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| Institution: | LIAO Chuan-yu,HUANG Zheng-gu,CHEN Tiang-ang,LI Tong-xin,WAN Dong-yong,RAO Xia,XU Yan,HOU Yi,ZHONG Min,YAN Xiao-feng Chongqing Infectious Disease Medical Center,Chongqing 400036,China |
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| Abstract: | Objective To investigate the clinical drug resistance of Mycobacterium tuberculosis in our center.Methods Mycobacterium tuberculosis was cultured by BACT/ALERT3D.L-J absolute concentration method was used for Mycobacterium tuberculosis strain identification and drug sensitivity test.Results Among the 1916 Mycobacterium tuberculosis strains,at least one-resistance drug was 62.8%(1204 strains),MDR was 24.1%(462 strains),XDR was 4.0%(76 strains).Drug resistance rates showed: INH was 40.5%(776 strains),RFP was ... |
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| Keywords: | MDR XDR |
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