| 神经梅毒12例临床分析 |
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| 引用本文： | 许庆芳,赖维,陆春,朱国兴,欧风仙,杨素莲,顾有守. 神经梅毒12例临床分析[J]. 中国皮肤性病学杂志, 2006, 20(3): 161-162 |
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| 作者姓名： | 许庆芳 赖维 陆春 朱国兴 欧风仙 杨素莲 顾有守 |
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| 作者单位： | 中山大学第三附属医院皮肤科,广东,广州,510630 |
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| 摘 要： | 目的分析神经梅毒的临床特征和早期诊断依据。方法对12例神经梅毒患者的临床资料进行了回顾性分析。结果5例有症状神经梅毒既往未接受驱梅治疗,临床表现多样。7例无症状神经梅毒接受首次驱梅治疗的时间较迟,表现为血清固定或血清复发。10例在治疗后1~6月复查脑脊液的各项指标,白细胞计数和蛋白含量均下降或转阴,而脑脊液(CSF)-VDRL试验仅2例转阴。结论未能早期发现和治疗梅毒是导致神经梅毒的重要因素。神经梅毒的诊断目前尚无金标准。脑脊液白细胞计数与蛋白含量是监测神经梅毒疗效的较敏感指标。
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| 关 键 词： | 神经梅毒 |
| 文章编号： | 1001-7089（2006）03-0161-02 |
| 收稿时间： | 2005-06-06 |
| 修稿时间： | 2005-06-062005-12-13 |
Clinical Analysis on 12 Cases of Neurosyphilis |
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| XU Qing-fang, LAI Wei, LU Chun, et al. Clinical Analysis on 12 Cases of Neurosyphilis[J]. The Chinese Journal of Dermatovenereology, 2006, 20(3): 161-162 |
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| Authors: | XU Qing-fang LAI Wei LU Chun et al |
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| Affiliation: | Department of Dermatology ,the third affiliated Hospital ,Zhongshan university, Guangzhou 510630, China |
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| Abstract: | Objective To study the clinical features of neurosyphilis and to find clues for early diagnoses.Methods Clinical data of 12 cases were analyzed.Results 5 cases with neurologic symptoms hadn't been treated once,their clinical manifestations were variable.7 cases of asymptomatic neurosyphilis got their initial treatment very late,and exhibited serofast state or serologic relapse.The white-cell count and protein of cerebrospinal fluid(CSF) decreased or turned negative among 10 cases after treatment,wheras 2 cases of CSF-VDRL was negative.Conclusion The failure to be diagnosed and treated early is the important cause of neurosyphilis.There is no golden standard available now in diagnosing neurosyphilis.The white-cell count and protein of cerebrospinal fluid are sensitive in evaluating the efficiency of treating neurosyphilis. |
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| Keywords: | Neurosyphilis |
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