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心脑致宝平的提取工艺
引用本文:夏超,孙兴华,刘媛,石金城.心脑致宝平的提取工艺[J].蚌埠医学院学报,2012,37(8):988-989.
作者姓名:夏超  孙兴华  刘媛  石金城
作者单位:南京工业大学,江苏省药物研究所,江苏,南京,210009;南京工业大学,江苏省药物研究所,江苏,南京,210009;南京工业大学,江苏省药物研究所,江苏,南京,210009;南京工业大学,江苏省药物研究所,江苏,南京,210009
摘    要:目的:研究心脑致宝平中生山楂、银杏叶、酒制大黄三味药材的提取工艺.方法:药材用乙醇提取,并以总蒽醌含量为指标,采用正交试验法对提取工艺进行优选.结果:加热温度是影响浸提效果的主要因素,其次为提取时间、提取次数,溶剂倍数影响最小.最佳提取工艺条件为6倍的70%乙醇浸提3次,每次1.5 h,提取温度为70℃.结论:正交试验法对心脑致宝平的提取工艺进行优化,有效提高总蒽酮的提取含量.

关 键 词:心脑致宝平  总蒽醌  正交试验  提取工艺

The study of extraction technology of xinnaozhibaoping
XIA Chao , SUN Xing-hua , LIU Yuan , SHI Jin-cheng.The study of extraction technology of xinnaozhibaoping[J].Journal of Bengbu Medical College,2012,37(8):988-989.
Authors:XIA Chao  SUN Xing-hua  LIU Yuan  SHI Jin-cheng
Institution:(Nanjing University of Technology,Jiangsu Provincial Institute of Materia Medical,Nanjing Jiangsu 210009,China)
Abstract:Objective:To study the extraction processes of fructus crataegin,ginkgo biloba L and rheum palmatum L of xinnaozhibaoping.Methods:Medicinal materials were extracted with ethanol and the content of anthraquinones were setted as standard.The extraction technology were optimized through orthogonal design.Results:The heating temperature was the main factor of influence extraction effect,followed by extraction time,extraction times and the solvent multiples were the least affect.Six times of 70% ethanol extracting for 3 times(every time for 1.5 hours) at 70 ℃ was the optimum extraction condition.Conclusions:The optimum xinnaozhibaoping extraction from orthogonal design can effectively improve the content of anthraquinones.
Keywords:xinnaozhibaoping  anthraquinones  orthogonal design  extraction technology
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