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经鼻间歇正压通气治疗新生儿呼吸窘迫综合征的疗效观察
引用本文:陈信,潘家华,丁周志,徐兵,夏群.经鼻间歇正压通气治疗新生儿呼吸窘迫综合征的疗效观察[J].蚌埠医学院学报,2012,37(5):541-543,547.
作者姓名:陈信  潘家华  丁周志  徐兵  夏群
作者单位:安徽医科大学附属省立医院,儿科,安徽,合肥,230001;蚌埠医学院第一附属医院,儿科,安徽,蚌埠,233004;安徽医科大学附属省立医院,儿科,安徽,合肥,230001;蚌埠医学院第一附属医院,儿科,安徽,蚌埠,233004
摘    要:目的:观察经鼻间歇正压通气(NIPPV)在新生儿呼吸窘迫综合征(NRDS)中的应用效果。方法:将48例NRDS患儿随机分为NIPPV组(25例)和经鼻持续气道正压通气(NCPAP)组(23例),观察比较2组治疗的成功率、治疗的时间、治疗前后动脉血气变化、氧合指数及并发症。结果:NIPPV组治疗成功率为72.0%,高于NCPAP组的43.5%(P0.05),NIPPV组治疗后1 h的动脉氧分压、氧合指数的升高显著大于NCPAP组(P0.05)。结论:NIPPV作为初始通气模式治疗NRDS是可行的,且疗效优于NCPAP。

关 键 词:呼吸窘迫综合征  婴儿  新生  疾病  经鼻间歇正压通气  持续气道正压通气

Effects of nasal intermittent positive pressure ventilation intreatment for neonates respiratory distress syndrome
CHEN Xin , PAN Jia-hua , DING Zhou-zhi , XU Bing , XIA Qun.Effects of nasal intermittent positive pressure ventilation intreatment for neonates respiratory distress syndrome[J].Journal of Bengbu Medical College,2012,37(5):541-543,547.
Authors:CHEN Xin  PAN Jia-hua  DING Zhou-zhi  XU Bing  XIA Qun
Institution:1.Department of Pediatrics,Anhui Provincial Hospital Affiliated to Anhui Medical University,Hefei Anhui 230001;2.Department of Pediatrics,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China)
Abstract:Objective:To evaluate the effects of nasal intermittent positive pressure ventilation(NIPPV) in treatment for neonates respiratory distress syndrome(NRDS). Methods:Forty-eight neonates with NRDS were randomly divided into NIPPV group(25 cases) and nasal continuous positive airway pressure(NCPAP) group(23 cases).The success rates,treatment time,the changes of arterial blood gas before and after treatment,oxygen index and complications of two groups were observed. Results:The treatment success rates of NIPPV group(72.0%) were higher than NCPAP group(43.5%)(P<0.05).The arterial oxygen partial pressure oxygen and index of NIPPV group were significantly higher than that of NCPAP group at 1 hour after treatment. Conclusions:The treatment for NRDS with NIPPV is feasible,and the effects of NIPPV on NRDS are better than NCPAP.
Keywords:respiratory distress syndrome  infant  newborn  diseases  nasal intermittent positive pressure ventilation  nasal continuous positive airway pressure
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