脑卒中急性期抑郁的发生率及其相关因素分析

目的:探讨脑卒中急性期卒中后抑郁(post-stroke depression,PSD)的发生率及其相关因素,为PSD的干预提供依据。方法:采用自制的一般情况调查表对125例脑卒中患者进行调查,根据17项汉密尔顿抑郁量表评分分为PSD组41例和非PSD组84例,并用神经功能缺损量表、日常生活活动量表进行评估。结果:PSD发生率为32.80%,患者的性别、年龄、经济状况、病灶部位、数量、神经功能缺损程度和日常生活活动能力受损情况均与PSD发生有关,差异有统计学意义(P0.05～P0.01),而文化程度、婚姻状况、脑卒中性质与PSD的发生均无明显关系(P0.05)。结论:脑卒中急性期PSD的发生率较高,以轻、中度抑郁为主,且相关因素较多。

Analysis of the incidence and relative factors of post-stroke depression at acute stage of cerebral stroke

Objective:To explore the incidence and relative factors of post-stroke depression(PSD) at acute stage of cerebral stroke,so as to provide a basis for intervening PSD.Methods:One hundred and twenty-five cases with cerebral stroke were investigated by a self-designed questionnaire,divided into PSD group(41 cases) and non-PSD group(84 cases) according to the score of 17-item Hamilton depression rating scales,and evaluated using neurologic deficit scale and activities of daily living scale.Results:The incidence of PSD was 32.80%.Sex,age,economical status,location of damages,number of lesions,neurologic deficits and activities of daily living of patients were related with PSD,and its differences were statistical significance(P<0.05-P<0.01).But there were no significant differences in levels of education,marital status and nature of stroke(P>0.05).Conclusions:The incidence of PSD of patients with cerebal stroke at acute stage is high,most PSD patients are mild and moderate and influenced by many factors.