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溶栓治疗后脑卒中患者应用他汀类药物疗效分析
引用本文:韦宁,欧世宁,韦英海,黎彬如.溶栓治疗后脑卒中患者应用他汀类药物疗效分析[J].蚌埠医学院学报,2012,37(4):431-432.
作者姓名:韦宁  欧世宁  韦英海  黎彬如
作者单位:广西民族医院,神经内科,广西,南宁,530001;广西民族医院,神经内科,广西,南宁,530001;广西民族医院,神经内科,广西,南宁,530001;广西民族医院,神经内科,广西,南宁,530001
摘    要:目的:探讨在脑卒中患者经溶栓治疗后,他汀类药物的应用问题及其疗效。方法:服用或未服用他汀类药物的经溶栓治疗后脑卒中患者共9例,根据美国国立卫生院卒中量表(NIHSS)及改良Rankin评分(modified Rankin scale,mRS)评分来评价患者不同时期的脑功能恢复情况。结果:脑卒中急性期服用他汀者发病48 h NIHSS评分下降较未用他汀者明显(P0.01),发病3个月mRS评分0~2分者4例,无病死病例(P0.01)。结论:在接受溶栓治疗的脑卒中患者中,他汀类药物在急性期的应用可促进发病后脑功能的恢复。

关 键 词:脑血管意外  溶栓治疗  他汀类药物

The curative effects of statin on stroke patient with thrombolysis treatment
WEI Ning , OU Shi-ning , WEI Ying-hai , LI Bin-ru.The curative effects of statin on stroke patient with thrombolysis treatment[J].Journal of Bengbu Medical College,2012,37(4):431-432.
Authors:WEI Ning  OU Shi-ning  WEI Ying-hai  LI Bin-ru
Institution:(Department of Neurology,Guangxi Minzu Hospital,Nanning Guangxi 530001,China)
Abstract:Objective:To assess the curative effects of statin drugs on stroke patient with thrombolysis treatment.Methods:Brain function recovery condition of 9 stroke cases with thrombolysis treatment taking or no-taking statin was evaluated during different periods according to Modified Rankin scale(mRS) and Nationel Institutes of Health Stroke scale(NIHSS).Results:The NIHSS scores of cases who took statin were significantly lower than that of no-taking statin at 48 hours(P<0.01).There were 4 cases′ mRS scores between 0-2 and no death with 3 months statin treatment.Conclusions:statin treatment can promote brain function recovery of stroke patient with thrombolysis treatment.
Keywords:cerebral vascular accident  thrombolysis treatment  statin
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