黄石地区解脲支原体和人型支原体感染情况和耐药性研究

目的:了解黄石地区解脲支原体(UU)和人型支原体(MH)感染情况和耐药性,为临床用药提供参考。方法:以支原体快速分离、鉴定计数以及多种抗生素药敏于一体的培养法检测UU和MH。结果:在350例疑似非淋菌性尿道炎患者中检出支原体阳性152例,阳性率43·43%。其中,男性146例,阳性标本52例,阳性率35·62%;女性204例,阳性标本100例,阳性率49·02%,女性检出率明显高于男性(χ2=6·222,P<0·05)。支原体对强力霉素、美满霉素、阿奇霉素、克拉霉素、司帕沙星、罗红霉素、交沙霉素、大观霉素、氧氟沙星、环丙沙星的耐药率分别为14·5%、16·4%、39·5%、44·1%、47·4%、49·3%、52·6%、53·9%、57·2%、74·4%。结论:黄石地区泌尿系感染的患者中支原体感染率较高,且女性感染高于男性;黄石地区支原体感染对强力霉素、美满霉素耐药低,而对氧氟沙星、环丙沙星耐药性高。

Infections and Antibiotic Resistance of Ureaplasma Urealytium and Mycoplasma Hominis in Huangshi Area

OBJECTIVE：To study the infections induced by ureaplasma urealyticum（UU） and mycoplasma hominis （MH） in Huangshi city and their antibiotic resistance for reference of clinical rational drug use.METHODS： UU and MH were detected by mycoplasma rapid culture and drug sensitivity test kit.RESULTS： Of the total 350 patients who were suspected as having nongonococcal urethritis（NGU）, 152（43.43% ） were positive in mycoplasma detection.52 of the total 146 male cases were positive（35.62%）, and 100 among the 204 female cases were positive（49.02% ）, with positive detection rate significantly higher than in male case（χ^2 = 6.222, P〈0.05） .The drug resistant rates of mycoplasma to doxycycline, minocycline, azithromycin, clarithromycin, sparfloxacin, roxithromycin, josamyein, spectinomycin, ofloxacin and ciprofloxacin were 14.5%, 16.4%, 39.5%, 44.1%, 47.4%, 49.3%, 52.6%, 53.9%, 57.2% and 74.4%, respectively.CONCLUSION： Mycoplasma infection rate was high among patients with urinary tract infection and it was more often seen in female than in male in Huangshi city.The drug resistant rates of mycoplasma were low to doxycycline and minocycline while high to ofloxacin and ciprofloxacin.