Primary glomerulonephritis in Hong Kong |
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Authors: | M. K. Chan P. D. Yin K. W. Chan |
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Affiliation: | (1) Department of Medicine, University of Hong Kong, Hong Kong;(2) Department of Pathology, University of Hong Kong, Hong Kong |
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Abstract: | The clinical presentation and natural history of 428 patients with biopsyproven primary glomerulonephritis were reviewed. Minimal change glomerulonephritis presented with the nephrotic syndrome and followed a benign course. Membranous glomerulonephritis took a slow downhill course. HBs antigenaemia was present in 30% of patients with membranous glomerulonephritis. Mesangiocapillary glomerulonephritis often presented with mixed nephritic-nephrotic syndrome and had a bad prognosis. No type II variant was detected. Mesangial IgA glomerulonephritis commonly presented with abnormal urinary sediments although 2.5% of adults presenting with the nephrotic syndrome without glomerular insufficiency had mesangial IgA disease. Mesangial IgA glomerulonephritis was an important cause of end-stage renal failure in Hong Kong. |
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