Ionic calcium and magnesium from pharmaceutical product BEROCCA effects on neuromuscular excitability |
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Authors: | Stratone Ana Stratone Carmen Chiruţă Roxana Zaharia D Căruntu Lidia Diaconu Mariana Stefancu Oana Topoliceanu Fl |
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Affiliation: | Universitatea de Medicin? ?i Farmacie Gr T Popa Ia?i, Facultatea de Medicin?, Disciplina de Explor?ri Func?ionale. |
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Abstract: | The important physiological role of calcium and magnesium ions is all over recognised, about a lot of enzymatic reactions. Magnesium deficit produce neuromuscular hyper-reactivity, psychic reactions, functional hypoparathyroidism, increase of K+ channels membranes permeability, while hypermagnesemia decrease Ach release from neuromuscular synapsis, with post-synaptic excitability decreasing. Using BEROCCA (Hoffman la Roche) 1 cp/day, 30 days at the teenagers with behaviour troubles and at a goup of pregnant women (trimester I-III) with paresthesia, irritability, sleeplessness, we observed an improve of clinical signs, increasing plasma Ca2+ and Mg2+. EEG and EMG prove the beneficial effects of pharmaceutical product BEROCCA. |
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