探讨血清锌、铜元素与体外受精-胚胎移植临床妊娠结局的关系

目的:探讨血清锌、铜元素与体外受精-胚胎移植(IVF-ET)临床妊娠结局的关系。方法:回顾性分析130个IVF-ET治疗周期的临床资料。结果:在130个周期中血清锌水平在HCG注射日最低,低于早卵泡期和黄体中期;血清铜在早卵泡期最低,黄体中期最高。临床妊娠组与未妊娠组相比,在早卵泡期、黄体中期的血清锌和铜元素差异无统计学意义(P0.05);HCG注射日血清锌、铜元素差异有统计学意义(P0.05)。结论:该研究旨在为改善IVF-ET临床妊娠结局提供一条新的思路。

The relationship between the serum zinc and copper concentration and the clinical pregnancy outcomes of fertilization in vitro and embryo transfer

Objective:To investigate the relationship between the serum zinc and copper concentration and the clinical pregnancy outcomes of in vitro fertilization and embryo transfer(IVF-ET).Methods:130 cycles of IVF-ET were retrospectively analyzed.Results:In the 130 cycles there were the lowest levels of serum zinc on the day of HCG administration compared to the early follicular and mid-luteal phases,and the lowest levels of serum copper on the early follicular phase but the highest levels on the mid-luteal phase.The differences of serum zinc and copper on the early follicular and mid-luteal phases between the pregnancy and no-pregnancy groups were statistically no significant(P>0.05),but the differences on the day of HCG administration were statistically significant(P<0.05).Conclusion:The study can provide a new thought to improve the IVF-ET clinical pregnancy outcomes.