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中国健康成人大脑中央前回质子磁共振波谱研究
引用本文:王惠芳,郎宁,宋红松,王力平,刘小璇,张俊,康德瑄,李选,樊东升. 中国健康成人大脑中央前回质子磁共振波谱研究[J]. 中国康复理论与实践, 2005, 11(5): 366-368
作者姓名:王惠芳  郎宁  宋红松  王力平  刘小璇  张俊  康德瑄  李选  樊东升
作者单位:1. 100083,北京市,北京大学第三医院神经科;100041,北京市,北京大学首钢医院神经内科
2. 100083,北京市,北京大学第三医院放射科
3. 100083,北京市,北京大学第三医院神经科
基金项目:卫生部部属(管)医疗机构临床学科重点项目基金(41623)
摘    要:目的 运用质子磁共振波谱(^1H-MRS)研究中国健康成人大脑中央前回脑组织代谢物的特点,为疾病研究提供正常参照。方法 对92名健康成年志愿者进行双侧中央前回^1H-MRS检测,对比分析其大脑中央前回脑组织的NAA/Cr、Cho/Cr和NAA/Cho值。结果 不同侧别和不同性别之间的NAA/Cr、Cho/Cr和NAA/Cho值均无显著性差异;NAA/Cr与年龄低度负相关,Cho/Cr与年龄低度正相关,NAA/Cho与年龄呈中度负相关。结论 建立了健康成人大脑中央前回脑组织代谢物的参照特点。

关 键 词:健康成人 中国 质子磁共振波谱 中央前回
文章编号:1006-9771(2005)05-0366-03
修稿时间:2005-01-13

Characteristics of proton magnetic resonance spectroscopy on precentral gyrus in 92 healthy Chinese adults
WANG Hui-fang,LANG Ning,SONG Hong-song,et al.. Characteristics of proton magnetic resonance spectroscopy on precentral gyrus in 92 healthy Chinese adults[J]. Chinese Journal of Rehabilitation Theory and Practice, 2005, 11(5): 366-368
Authors:WANG Hui-fang  LANG Ning  SONG Hong-song  et al.
Affiliation:WANG Hui-fang,LANG Ning,SONG Hong-song,et al.Neurological Department,Peking University third Hospital,100083 Beijing,China
Abstract:ObjectiveTo explore the characteristics of the metabolite concentrations of the precentral gyrus in healthy Chinese adults using proton magnetic resonance spectroscopy ( 1H-MRS).Methods 1H-MRS was carried out in 92 healthy Chinese adult volunteers. The metabolite ratios of NAA/Cr, Cho/Cr and NAA/Cho were compared and analysed.ResultsNo significant changes of NAA/Cr, Cho/Cr and NAA/Cho ratios were observed between the left and right precentral gyrus, nor between the male and female. However, the precentral gyrus NAA/Cr and NAA/Cho ratios were decreased gradually with aging and Cho/Cr ratios were increased gradually with aging.ConclusionThe characteristics of the precentral gyrus metabolite concentrations in healthy Chinese adults have been obtained.
Keywords:healthy adults  Chinese  precentral gyrus  proton magnetic resonance spectroscopy
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