Evaluation of quantitative variation of secondary metabolites in Bergenia ciliata (Haw.) using high performance thin layer chromatography |
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摘 要: | Dear Editor: Therapeutically active metabolite contents in a med- icinal plant vary in nature, which may impact on its therapeutic efficacy. Bergenia (Saxifragaceae) is an evergreen perennial herb widely distributed in Central and East Asia with about 30 species reported worldwide. It grows at a range of altitudes from the Khasia hills at 400 feet to the temperate Himalayas from Kashmir to Bhutan at 7,000-10,000 feet. Its distribution over a wide range of altitudinal zones makes it a good candidate for studying variations in its metabolic profiles under different climatic conditions. Bergenin (C-glycoside of 4-O-methyl gallic acid) has been identified as a potent active secondary metabolite in Bergenia and other therapeutically active constituents including, among others, gallic acid (3,4,5 trihydroxybenzoic acid), (+) catechin, and gallicin (Fig. 1).
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关 键 词: | 岩白菜素 高效薄层色谱法 次生代谢物 活性次级代谢产物 山楂 变异 评价 治疗效果 |
收稿时间: | 2013 Nov 29 |
Evaluation of quantitative variation of secondary metabolites in Bergenia ciliata (Haw.) using high performance thin layer chromatography |
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Authors: | Nishi Srivastava |
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Institution: | Pharmacognosy and Ethnopharmacology Division, CSIR-National Botanical Research Institute; and Chemistry Division, Integral University, Lucknow 226001, India. |
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