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| 方药量效关系研究的关键问题与思考 | |
| 引用本文： | 仝小林,焦拥政,连凤梅,王跃生,傅延龄,徐国良,饶毅,余日跃,饶平凡,刘文科,郭允,彭智平,赵林华.方药量效关系研究的关键问题与思考[J].环球中医药,2012,5(6):401-404. |
| 作者姓名： | 仝小林 焦拥政 连凤梅 王跃生 傅延龄 徐国良 饶毅 余日跃 饶平凡 刘文科 郭允 彭智平 赵林华 |
| 作者单位： | 1. 中国中医科学院广安门医院内分泌科,北京,100053 2. 中国中医科学院广安门医院科研处,北京,100053 3. 中国中医科学院广安门医院临床药理基地,北京,100053 4. 中国中医科学院中药研究所 5. 北京中医药大学国际学院 6. 江西中医学院现代中药制剂教育部重点实验室(药理) 7. 中药固体制剂制造技术国家工程研究中心 8. 江西中医学院药学院药理室 9. 福州大学生物工程研究所 10. 中国中医科学院广安门医院分子生物学室,北京,100053 |
| 基金项目： | 国家重点基础研究发展计划(973计划) |
| 摘 要： | "中医不传之秘在药量",方药剂量直接影响中医药临床疗效。开展方药量效关系的研究的重要目标在于指导临床合理用量,提高中医药临床疗效。本文就方药量效关系研究的核心概念:"随证施量"及"剂量阈"进行初步阐释,并对方药量效关系研究方法学研究体系的构建及方药剂量理论基本框架等相关问题进行探讨。由于中医方药本身的复杂性,方药量效关系研究中也存在诸多难点和谜团,亟待学者们深入研究,共同探索。 |
| 关 键 词： | 量效关系 方药 随证施量 剂量阈 |
Some thoughts about the key points in the research of the dose-response relationship |
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| Institution: | TONG Xiao-lin, JIAO Yong-zheng, LIAN Feng-mei,et al. Department of Endocrinology, Guang′an men Hospital of CACMS, Beijing 100053,China |
| Abstract: | The dosage is thought as the secret of TCM, which affects the clinical effect of TCM directly. The purpose of the dose-response relationship research of TCM is to look for the best or reasonable dosage when treating some diseases, and improves the effects of TCM. There are two important points about the key definitions of the dose-response relationship research, Sui Zheng Shiliang (dosage differentiatioan and treatment) and the dose range. Sui Zheng Shiliang means doctors select the dosage of some herbs in a formula according to the syndrome differentiation of the patients. And the dosage range research of some medica will give the doctor some references in practice. At the same time, some questions about the methodology and framework of the dose-response relationship research of TCM will be discussed in this paper. |
| Keywords: | Dose-response relationship TCM Sui Zheng Shiliang Dosage differentiatioan and treatment Dosage range |
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