Novel technique for airless connection of artificial heart to vascular conduits |
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Authors: | Jamshid H Karimov Shengqiang Gao Raymond Dessoffy Gengo Sunagawa Martin Sinkewich Patrick Grady Shiva Sale Nader Moazami Kiyotaka Fukamachi |
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Institution: | 1.Department of Biomedical Engineering/ND20,Lerner Research Institute, Cleveland Clinic,Cleveland,USA;2.Medical Device Solutions,Cleveland Clinic,Cleveland,USA;3.Perfusion Services,Miller Family Heart and Vascular Institute, Cleveland Clinic,Cleveland,USA;4.Department of Cardiothoracic Anesthesiology,Anesthesiology Institute, Cleveland Clinic,Cleveland,USA;5.Department of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure, Cardiac Transplantation and Mechanical Circulatory Support,Miller Family Heart and Vascular Institute, Cleveland Clinic,Cleveland,USA |
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Abstract: | Successful implantation of a total artificial heart relies on multiple standardized procedures, primarily the resection of the native heart, and exacting preparation of the atrial and vascular conduits for pump implant and activation. Achieving secure pump connections to inflow/outflow conduits is critical to a successful outcome. During the connection process, however, air may be introduced into the circulation, traveling to the brain and multiple organs. Such air emboli block blood flow to these areas and are detrimental to long-term survival. A correctly managed pump-to-conduit connection prevents air from collecting in the pump and conduits. To further optimize pump-connection techniques, we have developed a novel connecting sleeve that enables airless connection of the Cleveland Clinic continuous-flow total artificial heart (CFTAH) to the conduits. In this brief report, we describe the connecting sleeve design and our initial results from two acute in vivo implantations using a scaled-down version of the CFTAH. |
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