大肠癌同时伴肝转移67例临床治疗分析

目的探讨大肠癌同时伴肝转移的外科治疗效果。方法回顾性分析2003年1月至2007年12月67例大肠癌伴肝转移经外科手术治疗的临床资料。结果13例全肝多个转移灶病人行原发病灶切除加门静脉化疗泵植入术,余54例行原发灶和肝转移灶同期切除。本组术后1、2、3年生存率分别为91．0％（61／67）、71．6％（48／67）和40．3％（27／67）。生存时间最短为8个月,最长为57个月,中位生存期为30．2个月。结论大肠癌肝转移病人行原发灶和肝转移灶同期切除辅以局部及全身化疗,亦可取得满意效果。

Clinical analysis of 67 cases of simultaneous liver metastasis from colon cancer

Objective To explore the effect of surgical treatment on simultaneous liver metastasis from colon cancer. Methods The clinical data of 67 cases of simultaneous liver metastasis from co- lon cancer subject to surgical treatment from Jan. 2003 to Dec. 2007 in our hospital were analyzed. Results Thirteen patients with multiple liver metastases underwent resection of primary tumor and portal vein pump implantation, and the remaining 54 cases were treated with simultaneous resection of primary tumor and liver metastases. The 1-,2- and 3-year survival rate of all 67 patients was 91.0 %（61/67） ,71.6 %（48/67） ,40. 3% （27/67） respectively. The shortest survival time was 8 months and the longest survival time was 57 months with the median survival time being 30. 2 months. Conclusion Simultaneous resection of colon cancer primary tumor and liver metastases, supplemented with local and systemic chemotherapy, can achieve satisfactory results.